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Losartan, Especially as Nanoparticles, Eased Cerebellum Damage in Rats

MHD card showing a glowing emerald cerebellum with a tree-like inner branching pattern dotted with amber nanoparticle spheres and a faint rat silhouette, illustrating a rat study in which losartan eased toxin damage to the cerebellum.

In rats with toxin-damaged cerebellums, 4 weeks of the blood-pressure drug losartan reduced oxidative damage, inflammation and tissue injury. A nanoparticle version did better on several tissue and staining measures, but not on gene activity.1 Research Highlights A small rat experiment: 24 male rats in 4 groups of 6. Three groups received carbon tetrachloride (a …

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Microplastics & Nanoplastics Cross Blood-Brain Barrier within Hours & May Cause Damage

Microplastics and nanoplastics (MNPs) from the breakdown of plastic materials pollute the environment and make their way into the human body, raising concerns over potential health impacts. Research shows that microplastics and nanoplastics are able to cross the blood-brain barrier in mice within 2 hours of ingestion. Key Facts: Polystyrene nanoparticles with a size of …

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