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Naltrexone & Weight Loss: What Should You Expect?

Naltrexone is a chemical initially synthesized in 1963 and patented thereafter by the pharmaceutical company Endo Laboratories in 1967.  It is considered a substituted derivative of oxymorphone in that the tertiary amine methyl-constituent is replaced with an allyl group (specifically an N-cyclopropylmethyl group) – or a longer chain of carbon atoms.  It was initially approved …

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Naltrexone Side Effects & Adverse Reactions (List)

Naltrexone is a pure opioid receptor antagonist utilized principally for the treatment of alcohol and opioid dependence.  As an opioid receptor antagonist, naltrexone competitively binds to mu-opioid receptor (MOR) and kappa-opioid receptor (KOR) sites with higher affinity than opioid agonists, thereby attenuating receptor activation.  Should an individual administer an opioid agonist (e.g. morphine) while taking …

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