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qMRI Brain Aging Maps Myelin, Iron, and Water in 138 Adults

MHD featured image for qMRI brain aging maps of myelin, iron, and water.

A 2026 quantitative MRI preprint reanalyzed 138 healthy adults and found that multivariate modeling detected coordinated age-related shifts across myelin-sensitive, iron-sensitive, and water-sensitive brain maps.1 The signal was broad, but split-half validation weakened the result enough to keep it in the measurement-method lane rather than the clinical-test lane. Research Highlights 138 adults were reanalyzed: The …

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Methylone for Depression & PTSD: Rapid Neuroplastic Effects & More Targeted than MDMA (2024 Study)

In the search for rapid, effective treatments for Post-Traumatic Stress Disorder (PTSD), the exploration of psychoactive compounds like methylone presents a new frontier. Unlike traditional treatments, methylone has shown promising rapid-acting, robust, and long-lasting antidepressant-like and anxiolytic effects in preclinical studies. By comparing its effects with MDMA, a well-known compound with similar therapeutic potential, researchers …

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