mitophagy

Published research on mitophagy.

Neurodegenerative DiseasesJul 11, 2026

PINK1 and Parkin Link Parkinson’s Disease to Failed Mitochondrial Cleanup

A 2026 review ties the Parkinson’s disease genes PINK1 and parkin to damaged-mitochondria cleanup, from damage sensing and ubiquitin tagging to autophagy recruitment and lysosomal degradatio…

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DepressionFeb 18, 2024

PGAM5 Genetics & Depression via ATP Levels in the Prefrontal Cortex (2023 Mouse Study)

Major depressive disorder (MDD) is a complex and prevalent psychiatric condition that affects millions worldwide, yet its underlying mechanisms remain only partially understood. Recent resea…

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DepressionJan 5, 2024

Mitophagy & Depression: Mitochondrial Autophagy as an Antidepressant Target?

Depression is a pervasive mental health issue with complex origins and often inadequate treatment options. Recent studies have suggested that mitophagy, the process of selective mitochondria…

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