A 2026 multi-ancestry genome-wide association study of urinary aMT6s, a melatonin metabolite used as a proxy for overnight melatonin secretion, found 0 genome-wide significant loci in 11,744 people, even though 23 variants reached suggestive significance and 8 were supported by 2 analytic methods. Research Highlights No common variant dominated: the 2026 GWAS meta-analysis involving 11,744 …
In the intricate world of mental health, the rhythms of our body’s natural processes play a pivotal role, particularly the circadian rhythm of melatonin, a hormone primarily produced by the pineal gland. Recent research suggests that variations in melatonin’s circadian rhythm might not only distinguish between depression and bipolar disorder but also correlate with the …
Most people are unaware of the fact that bright light after sunset probably isn’t healthy, especially if you are suffering from insomnia, dealing with poor sleep quality, or a circadian rhythm disorder. For millions of years, humans functioned without artificial lights, TVs, and other electronics (e.g. cell phone screens). They relied solely on the sunlight …
When withdrawing from any antidepressant, most would agree that it’s best to taper. Tapering reduces the likelihood that you’ll endure protracted withdrawal symptoms, and gives your nervous system a slower readjustment to homeostatic functioning from being under the influence of a drug. Taking steps such as: maintaining a good diet for mental health, staying productive, getting …
Humans are meant to be awake when the sun comes up sleep when it sets – this is common sense, yet highly important to maintain healthy functioning. Although most people are able to adhere to the biological instinct of sleeping when it’s dark, and waking when it’s light, some people are assigned to “shift work.” …