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Buspar (Buspirone) For Depression: Exploring The Antidepressant Potential

Buspar (Buspirone) is a drug of the azapirone chemical classification that was engineered and patented in the 1970s by Mead Johnson.  It was later acquired by the pharmaceutical company Bristol-Myers Squibb and approved by the FDA in 1986 for the treatment of generalized anxiety disorder (GAD).  What’s unique about buspirone compared to other anxiolytics such …

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Mirapex (Pramipexole) For Depression: An Effective Antidepressant?

Mirapex (Pramipexole) is a drug that is approved by the FDA for the treatment of Parkinson’s disease and RLS (restless leg syndrome).  Classified as a dopamine receptor agonist, pramipexole elicits partial or full agonism upon D3 receptors, D2 receptors (2L/2S), and D4 receptors.  Interestingly, pramipexole also appears to modify mitochondrial function, and to a negligible …

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NSI-189 For Depression: New Drug Grows Hippocampus

Individuals diagnosed with major depression often are found to have reduced volume within their hippocampus. The hippocampus is a small region of the brain that is responsible for regulating various memory and spatial navigation functions. It is also believed to play a pivotal role in the regulation of mood. Modern day antidepressants such as SSRIs …

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Do Antidepressants Work?

Depression is a very common emotion that everyone experiences at some point in life. In some cases depression is triggered by external events and environmental factors. In other cases, no matter how good someone’s environment or healthy their habits, they feel a depression that they cannot shake. This inevitably leads people to search for a …

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