MentalHealthDaily

Bilateral Anterior Capsulotomy (BAC) for Treatment-Resistant Depression & OCD (2023 Case Reports)

by GLOOM

In the relentless pursuit of effective treatments for mental disorders, neurosurgery offers a glimmer of hope where traditional methods falter. Bilateral anterior capsulotomy (BAC), a neurosurgical procedure, emerges as an option for patients with treatment-resistant depression (TRD) and obsessive-compulsive disorder (OCD), offering substantial relief with minimal side effects. Highlights: Bilateral Anterior Capsulotomy (BAC) is a …

4 Depression Subtypes Identified via PHQ-9 Tool: Affective, Somatic, Internalizing, Sensorimotor (2023 Study)

by GLOOM

Depression, a multifaceted mental health disorder affecting millions worldwide, has long been a challenge for both diagnosis and treatment. The standard method for evaluating depression in outpatient settings, the Patient Health Questionnaire-9 (PHQ-9), has traditionally been viewed as a unidimensional tool. However, recent research suggests that the complexities of Major Depressive Disorder (MDD) may be …

Psilocybin for Major Depression in Adults (2023 Evidence Review)

by GLOOM

The emerging research into psilocybin, a classical psychedelic, reveals its significant potential in treating Major Depressive Disorder (MDD). Historically used in spiritual and shamanic practices, psilocybin’s recent clinical studies have opened new avenues in mental health treatment, challenging traditional antidepressants like SSRIs. Highlights: Psilocybin’s Historical & Clinical Relevance: A natural compound used for millennia, recent …

Customized Transcranial Magnetic Stimulation (TMS) Protocols for Depression & Psychiatric Disorders Based on Personalized Neuroimaging (2023 Evidence)

by GLOOM

Recent advancements in neuroimaging and brain stimulation techniques, particularly Transcranial Magnetic Stimulation (TMS), are revolutionizing the treatment of psychiatric disorders. These technologies, leveraging our understanding of individual brain network architectures, offer the potential for highly personalized treatments. Highlights: Personalization of Treatment: Neuroimaging advancements allow for the personalization of brain stimulation targets, particularly in Transcranial Magnetic …

Esketamine Nasal Spray Effective Last Resort for Treatment-Resistant Depression (TRD)? (2023 Study)

by GLOOM

Treatment-resistant depression (TRD) represents a significant challenge in mental health care, often leaving patients and clinicians in a difficult position after traditional treatments fail. Recent studies, including a prospective, observational study at a leading medical center, have brought new hope in the form of esketamine, a novel antidepressant. Highlights: Esketamine’s Mechanism: Esketamine, the S-enantiomer of …

Analyzing Serum Biomarkers to Predict Antidepressant Efficacy in Depression (2023 Study)

by GLOOM

Depression, a complex and often debilitating mental health condition, affects millions globally. Despite advances in psychiatric medicine, finding the right treatment remains a challenge for many. A recent comprehensive study, however, is shedding light on this issue by examining the role of serum biomarkers in predicting the effectiveness of antidepressant therapy. Highlights: Innovative Approach: This …

Non-Directive Supportive Therapy (NDST) for Major Depression: Is It Effective? (2024 Review)

by GLOOM

Depression, a common yet complex mental health disorder, has various treatment options, including psychotherapies like Non-Directive Supportive Therapy (NDST). A recent meta-analysis sheds light on the effectiveness of NDST in treating depression, comparing it with control conditions and other therapies. Highlights: NDST has been identified as a moderately effective treatment for depression compared to control …