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Childhood Anxiety Linked to DNA Methylation and DMN-Limbic Development

MHD featured image for childhood anxiety, DNA methylation, and DMN-limbic network development.

A 2026 Singapore birth-cohort preprint found a conditional childhood-anxiety signal: the cord-blood DNA methylation component predicted less age-13 anxiety only in boys in the low DMN-limbic trajectory group from ages 4.5 to 10.5 years. The paper is useful for mapping developmental risk biology, but it is not a screening test and it does not show …

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Lisdexamfetamine (Vyvanse) Changes Brain Connectivity & Activation to Treat Binge Eating Disorder (2023 Study)

Binge-eating disorder (BED), characterized by recurrent episodes of overeating without compensatory behaviors, is a significant global health concern. Lisdexamfetamine dimesylate (LDX), the only drug approved for moderate to severe BED, is showing promise not just in reducing episodes but also in altering brain function in ways previously not fully understood. Through a groundbreaking study, researchers …

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