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Sleep Disorders vs. Systemic Immune-Inflammation Index (SII) in the U.S. Population (2023 Study)

Sleep and inflammation have long been topics of scientific inquiry, with a growing body of evidence underscoring their intricate relationship. The systemic immune-inflammation index (SII), a novel marker based on leukocyte parameters, has emerged as a significant indicator of systemic inflammation. A recent study explored the association between sleep-related disorders and SII, revealing intriguing connections …

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Schizophrenia vs. Immune System Activation: Cellular Signatures & Genetic Analysis (2023 Study)

Schizophrenia (SCZ) is a complex psychiatric disorder that affects millions worldwide, with symptoms ranging from hallucinations to disorganized thinking. Research into the causative factors of SCZ has expanded into the realm of immunology, examining how immune system interactions with the brain might influence the development and progression of the disorder. A recent comprehensive study using …

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Cytokine Profiles in Major Depression (Low IL-17C) & Comorbid Anxiety (2024 Study)

Recent studies have shed light on the intricate relationship between cytokines—proteins crucial for cell signaling in the immune system—depression, and anxiety. This exploration is pivotal in unveiling the potential biomarkers and therapeutic targets for major depressive disorder (MDD), particularly in patients experiencing their first episode and those untreated with drugs, with or without comorbid anxiety. …

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Fatty Acid Sensor GPR120 (FFAR4) Treatment Target for Anxiety & Neuroinflammation (2023 Study)

In the quest to understand the intricate relationship between our diet, brain, and behavior, scientists are turning their focus to a unique receptor, GPR120. This protein, known for interacting with long-chain fatty acids like omega-3s, is shedding new light on how our body’s inflammation and metabolism can directly affect our mental health. By exploring GPR120’s …

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Alzheimer’s Disease, Microglia, & Environmental Risk Factors (2024 Evidence)

Alzheimer’s disease, a debilitating neurodegenerative condition, is influenced significantly by a blend of genetic, environmental, and lifestyle factors. New research focuses on environmental risk factors and microglia (the brain’s immune cells) for Alzheimer’s development. Highlights: Alzheimer’s Disease and Microglia: Alzheimer’s is characterized by cognitive decline, and microglia play a crucial role in its pathogenesis, acting …

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