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Sex Differences of Gut Bacteria (Microbiome) in Major Depression (2024 Review)

The intricate relationship between the gut microbiome and major depressive disorder (MDD) is gaining significant attention within the scientific community. Emerging research highlights sex-specific disparities in the gut microbiome’s composition and its potential impact on MDD, pointing towards the necessity of integrating sex as a biological variable in future studies. Highlights: Sex Disparities in MDD: …

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Chronic Stress Alters the Gut Microbiome & Intestinal Barrier in Mice with Sex-Specific Effects (2023 Study)

The gut-brain axis, a complex communication network linking the gastrointestinal tract and the brain, plays a pivotal role in maintaining both mental and physical health. Recent studies illuminate how chronic stress disrupts this intricate system, particularly affecting the intestinal barrier in the jejunum, and contributes to the pathogenesis of Major Depressive Disorder (MDD). This emerging …

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Gut Bacteria Composition in Major Depression vs. Healthy Controls & Antidepressant Treatment (2024 Study)

Depression, a multifaceted disorder characterized by pervasive sadness and lack of interest, extends beyond the brain to implicate the entire body, including the gut. Recent research has illuminated the significant role that gut microbiota plays in Major Depressive Disorder (MDD), suggesting a complex interplay between our microbial inhabitants and mental health. Highlights: Gut Microbiota & …

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Probiotics & Synbiotics for the Metabolic Side Effects of Psychiatric Medications: Are They Effective? (2024 Review)

Patients with severe mental illnesses (SMI), such as schizophrenia and chronic depression, often face the challenge of managing weight gain and metabolic complications, side effects commonly associated with antipsychotics and antidepressants. These medications are known to induce increased appetite and weight gain, leading to long-term metabolic syndromes. Recent studies have evaluated into the role of …

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Ketogenic Diet for ADHD Treatment via Gut Microbiome Modulation (2023 Study)

Attention deficit hyperactivity disorder (ADHD) is a behavioral disorder commonly found in children, characterized by symptoms such as inattention, hyperactivity, and impulsivity. Recent research has revealed a connection between gut microbiota and neuropsychiatric disorders like ADHD. A new study suggests that the ketogenic diet could provide therapeutic benefit in ADHD by modulating gut bacteria and …

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Gut Microbiome & Social Anxiety Disorder: Abnormal Bacterial Composition (2023 Study)

Recent scientific endeavors have unveiled a fascinating link between our gut microbiome and mental health, with a focus on Social Anxiety Disorder (SAD). This complex relationship, highlighting the role of microbial inhabitants in our gut in influencing our brain and behavior, marks a significant shift in understanding mental disorders. Highlights: Social Anxiety Disorder (SAD) affects …

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Fecal Microbiota Transplantation (FMT) for Depression Treatment: 2 Case Reports (Pilot Study)

Fecal microbiota transplantation (FMT) aims to modify the gut microbiome and holds promise as a new treatment approach for major depressive disorder (MDD). Early case studies report improvements in depressive symptoms following fecal microbiota transplantation (FMT), but larger controlled trials are needed to substantiate its efficacy. Key Facts: Two patients with long-standing major depression received …

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