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1 mg Guanfacine for Self-Harm Thoughts in ADHD-PTSD-BPD Case

MHD featured image for 1 mg guanfacine and self-harm thoughts in complex ADHD, PTSD, BPD, and ASD comorbidity.

A 2026 case report linked 1 mg nightly guanfacine modified-release to first-ever cessation of intrusive deliberate self-harm thoughts in a 16-year-old with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD) traits, borderline personality disorder (BPD) traits, and post-traumatic stress disorder (PTSD). The same case became more interesting after the patient stopped taking guanfacine and the self-harm …

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Safest Psychiatric Drugs: Low Risk, Effective Medications

Reports suggest that nearly 20% of all people in the United States are taking a psychiatric drug.  This means that 1 out of every 5 people you see is on some sort of mind-altering medication.  Although many of these drugs are marketed as being “safe and effective” for conditions like ADHD, anxiety, bipolar disorder, depression, …

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Guanfacine For ADHD: An Effective Treatment & Adjunct

Guanfacine is a drug that was developed primarily for the treatment of hypertension (high blood pressure).  It has been proven as an effective medication to reduce both systolic and diastolic blood pressure via its effect on Alpha-2 adrenergic autoreceptors.  It functions by stimulating these receptors (as an agonist) and reducing activation of the sympathetic nervous …

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