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Fetzima (Levomilnacipran) & Weight Loss vs. Gain

Fetzima (Levomilnacipran) is a medication prescribed for the treatment of major depressive disorder in adults.  Although it is similar to the drug Savella (Milnacipran), Fetzima exhibits unique pharmacodynamics in that it functions as a serotonin-norepinephrine reuptake inhibitor (SNRI) with a 2-fold affinity for norepinephrine reuptake inhibition – relative to serotonin reuptake inhibition. In other words, …

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Hydrochlorothiazide & Weight Loss: How Much To Expect?

Hydrochlorothiazide is a diuretic medication prescribed for the treatment of hypertension and edema (fluid accumulation and retention in bodily tissues) resulting from various medical conditions and prescription medications (e.g. corticosteroids).  Other medical conditions for which hydrochlorothiazide is sometimes prescribed to treat include: congestive heart failure, diabetes insipidus, renal tubular acidosis, and kidney stones (as a …

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Depakote Causes Weight Gain In Over 50% of Users?

Depakote (divalproex sodium) is a medication regularly prescribed for the management of epilepsy, bipolar disorder, and migraine headaches.  Other medical conditions for which Depakote is occasionally utilized as a complementary (i.e. adjunct) therapy include: AIDS, cancer, dopamine dysregulation syndrome (associated with Parkinson’s disease), schizophrenia. Most who are familiar with this drug understand that Depakote (divalproex …

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Does Propranolol Cause Weight Gain?

Propranolol, sometimes referred to as “Inderal” (brand name), is a non-cardioselective sympatholytic beta blocker that was first synthesized by British scientist James Black in 1964.  As a non-selective beta blocker, propranolol prevents endogenous catecholamines (e.g. norepinephrine and epinephrine) from activating Beta-1 and Beta-2 adrenergic receptors within the CNS (central nervous system) and PNS (peripheral nervous …

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Why Prednisone Causes Weight Gain (And What To Do About It)

Prednisone is a synthetic pregnane corticosteroid that was first identified in 1950 by the American microbiologist Arthur Nobile, and thereafter, synthesized in 1955 by the Schering Corporation.  As a synthetic derivative of cortisone, prednisone acts by mimicking the physiologic effects of cortisol, the chief endogenous hormone secreted by the adrenal cortex when the body is …

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Does Mirena Cause Weight Gain? (What You Should Know)

Mirena is a small T-shaped intrauterine device (IUD) that releases the progestin hormone “levonorgestrel” to prevent: pregnancy, heavy menstrual periods, and/or excessive build of the uterus lining in persons on estrogen replacement therapy.  When properly inserted within the uterus, Mirena is programmed to release 20 micrograms of levonorgestrel per day, and is expected to remain …

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Does Buspar Cause Weight Gain or Loss?

Buspar (buspirone) is a medication [of the azapirone classification] that’s most commonly administered for the treatment of generalized anxiety disorder (GAD).  Although Buspar is solely approved by the FDA for the treatment treat anxiety disorders, it is occasionally prescribed for other medical conditions like: major depressive disorder (as a standalone or adjunct); cerebellar ataxia; sexual …

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