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Effects of Pramipexole on Reward Learning: Possible Depression Treatment? (2023 Study)

In a significant stride toward understanding and treating depression, a 2023 study meticulously investigates the effects of pramipexole, a dopamine D2-like agonist, on reward learning. By exploring its impact on healthy volunteers through rigorous behavioral and neural assessments, the research offers groundbreaking insights into how this drug (occasionally used in depression) could revolutionize therapeutic strategies …

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Reward Deficiency Syndrome: Causes, Symptoms, Treatment

Reward deficiency syndrome (RDS) is a psychological theory first noted by Kenneth Blum in 1996. It is characterized by reward-seeking behavior and/or addictions, stemming from genetic variations, most notably resulting from those carrying the D2A1 allele. People carrying the A1 allele tend to have insufficient numbers of D2 receptors in their brain, resulting in lack …

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