MentalHealthDaily

Gene Editing with CRISPR/Cas9 to Treat Corticosteroid-Induced Neuropsychiatric Disorders (2023 Review)

The widespread use of corticosteroids (CCSs) across the globe for treating inflammatory conditions has led to an increased incidence of corticosteroid-induced neuropsychiatric disorders (NPDs), raising significant public health concerns. These disorders range from depression and anxiety to severe cognitive changes, challenging the medical community to find effective treatments. The exploration of genetic and epigenetic factors …

Top 10 Pharma Drugs & Medications That Cause Weight Gain (2012-2021)

by GLOOM

It is estimated that 40% of U.S. adults are obese – and this figure is projected to continue growing. One potential reason for weight gain and a possible catalyst for obesity is use of pharmaceutical drugs (i.e. medications). Medication-induced weight gain poses a significant challenge in healthcare, affecting both patient well-being and treatment adherence. Key …

Why Prednisone Causes Weight Gain (And What To Do About It)

by GLOOM

Prednisone is a synthetic pregnane corticosteroid that was first identified in 1950 by the American microbiologist Arthur Nobile, and thereafter, synthesized in 1955 by the Schering Corporation. As a synthetic derivative of cortisone, prednisone acts by mimicking the physiologic effects of cortisol, the chief endogenous hormone secreted by the adrenal cortex when the body is …