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Stress Internalization Predicts Memory Decline in Older Chinese Americans

Editorial card showing an older Chinese American adult and a memory-decline trajectory, illustrating the PINE cohort finding that stress internalization predicts cognitive decline.

A 2025 longitudinal analysis of 1,528 older Chinese Americans by Chen et al. in the Journal of Prevention of Alzheimer’s Disease says something more specific than “stress causes Alzheimer’s”: it isn’t the count of stressors that tracks memory decline — it’s a latent trait the authors call stress internalization, a bundle of high perceived stress, …

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Statins and Dementia Risk: No Long-Term Signal in 322,358 Patients

Statins do not look like a dementia-prevention drug, but they do not look like a dementia hazard either. In 322,358 Kaiser Permanente Northern California patients followed for an average of 11.8 years, dementia diagnoses rose right after statins were started, then flattened: after the first year, the hazard ratio for Alzheimer’s disease and related dementias …

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Alcohol & Brain Volume in Older Adults: Cortical Thinning & White Matter Loss in Heavy Drinkers (250g/Week) (2023 Study)

Alcohol’s effects on the brain, especially among the elderly, have long been a subject of scientific inquiry. A recent study from Gothenburg, Sweden, provides new insights into how varying levels of alcohol consumption impact brain structure in individuals aged 70 and over. This research sheds light on the relationship between alcohol intake and the aging …

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Ultra-Processed Foods (UPF) Linked to Increased Alzheimer’s Disease Risk (2023 Review)

In the modern dietary landscape, ultra-processed foods (UPFs) have become a staple in many diets, celebrated for their convenience and palatability. However, emerging research reveals a concerning association between UPF consumption and increased risk of Alzheimer’s disease (AD), a leading cause of dementia. Highlights: Strong Link: Recent systematic reviews indicate a strong link between high …

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Antidepressants & Dementia Risk in Elderly Users: SSRIs vs. TCAs (2024 Study)

Recent research has uncovered connections between the use of antidepressants and the risk of developing dementia in the elderly. This complex relationship, marked by varying results and considerations, is becoming a critical area of study in geriatric medicine and mental health. In light of these findings, it is crucial to delve into the nuances of …

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Genetics & Age-Related Cognitive Decline: Insights from TOMORROW Trial (2024 Study)

In a study utilizing data from the TOMMORROW trial, researchers have embarked on a novel exploration of genetic associations with cognitive change in older individuals. Employing a genome-wide association study (GWAS) approach, they’ve identified specific genetic variants linked to cognitive dynamics, providing new insights into the genetic underpinnings of cognitive change with aging. Highlights: Novel …

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