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Anti-CGRP Monoclonal Antibodies to Prevent Chronic Migraine (2023 Review)

Migraine, a primary headache disorder, significantly impacts the quality of life of millions worldwide. In recent years, the focus has shifted toward developing targeted therapies, particularly monoclonal antibodies (mAbs) against the calcitonin-gene-related peptide (CGRP), to prevent chronic migraine attacks. A relatively recent comprehensive network meta-analysis (NMA) evaluated the efficacy and safety of various anti-CGRP mAbs, …

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Botox For Migraines: Facial Injections To Prevent Headaches?

Botox (onabotulinumtoxinA) is a purified toxin derived from fermentation of the anaerobic bacterium Clostridium botulinum type A.  Most people are familiar with the cosmetic application of Botox whereby it is injected into facial muscles with the intent of reducing wrinkles, enhancing skin smoothness, and improving facial aesthetics. However, in addition to its cosmetic use, Botox …

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