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Risperidone Stroke Risk in Dementia: HR 1.28 Across CVD Subgroups

Conceptual illustration of cerebral blood vessels and a pill, representing risperidone-associated stroke risk in dementia patients.

The risperidone-stroke link in dementia is one of the longest-running safety signals in geriatric psychiatry, anchoring the FDA’s 2005 black-box warning on atypical antipsychotic mortality. Popular framing reduces it to “antipsychotics cause stroke in dementia” — a true sentence that flattens a multi-axis decision. Choma’s 2025 analysis of UK primary care records is the largest …

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Psychological Burnout & Increased Risk of Cardiovascular Disease (CVD) (2024 Review)

Burnout, once a fringe topic relegated to the backburners of occupational health discussions, has emerged as a critical public health crisis with far-reaching consequences. Beyond its immediate toll on mental health and workplace productivity, burnout’s insidious effects extend to one of the body’s most vital systems: the cardiovascular system. Highlights: Elevated Risk: Individuals experiencing burnout …

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Analyzing Cardiovascular Effects & Risks of Newer Antidepressants

Depression is a prevalent and serious condition in older adults and those with cardiovascular disease. Serotonin reuptake inhibitors (SSRIs) are commonly used to treat depression, but when they’re ineffective, alternative antidepressants must be considered. Key Facts: Depression in Older Adults and Cardiovascular Patients: Affects 15-20% of patients with coronary heart disease. Limitations of SSRIs: While …

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