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Empagliflozin for Depression: Effective Adjunct with SSRIs (2024 Clinical Trial)

Major Depressive Disorder (MDD) impacts millions globally, making it a significant public health challenge. Traditional treatments like Selective Serotonin Reuptake Inhibitors (SSRIs) don’t work for everyone, highlighting the need for innovative approaches. Recent clinical trials exploring the use of empagliflozin, a medication originally used to lower blood sugar in diabetes patients, have shown promising results …

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Insulin & Blood Sugar vs. Cognitive Function & Psychiatric Disorders (2023 Evidence)

Hyperglycemia, or high blood sugar, is more than a mere symptom of diabetes; it’s a complex condition that may significantly impact cognitive functions like memory and attention. While the association between diabetes and physical health complications is well known, there’s a growing body of research exploring how altered insulin signaling, a key feature of diabetes, …

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Fanapt (Iloperidone) & Weight Gain: What Should You Expect?

Fanapt (Iloperidone) is an antipsychotic that was approved in 2009 for the treatment of schizophrenia.  It functions similar to most current-market atypical antipsychotics in that it acts as an antagonist of the 5-HT2A receptor and D2 dopamine receptor.  It is thought to produce fewer extrapyramidal side effects (e.g. akathisia) compared to other antipsychotics. The drug …

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5 Oxaloacetate Benefits: How Supplementation Protects Your Brain & General Health

Oxaloacetate (or Oxaloacetic Acid) is an organic compound that is involved in many neurophysiological processes within your body.  It plays a key role in functions such as: amino acid synthesis, citric acid cycle, fatty acid synthesis, gluconeogenesis, glyoxylate cycle, and the urea cycle.  For example, oxaloacetate is considered an intermediate in the Kreb’s cycle prior …

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