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Pindolol For Depression: A Useful Antidepressant Adjunct?

Pindolol is a beta blocker initially synthesized by the pharmaceutical company Sandoz in the 1960s.  As of 1977 it received FDA approval for the management of hypertension and was sold under the brand name “Visken.”  Pharmacologically, pindolol acts as a non-selective beta blocker, meaning it competitively binds to all 3 beta-adrenergic receptor sites (Beta-1, Beta-2, …

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RNAi For Depression: siRNA Targets SERT & 5-HT1A for Antidepressant Effect

It seems as though society is on the verge of ushering in a new generation of treatment modalities for depression and other psychiatric conditions.  While most people turn to pharmaceutical drugs for major depressive disorder, approximately 1 out of 3 people fail to get sufficient symptomatic relief.  To make matters worse, many end up trying …

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