It seems as though society is on the verge of ushering in a new generation of treatment modalities for depression and other psychiatric conditions. While most people turn to pharmaceutical drugs for major depressive disorder, approximately 1 out of 3 people fail to get sufficient symptomatic relief. To make matters worse, many end up trying …
Saphris (Asenapine) is a drug that was approved by the FDA in 2007 for the treatment of schizophrenia and the manic phases of bipolar disorder. It functions by acting primarily on 5-HT2A serotonergic receptors and D2 dopaminergic receptors as an antagonist. It also elicits effects on a variety of other serotonergic receptors (5HT2B, 5HT2C, 5HT6, …
Perhaps you’ve heard of the fictional story “Flowers for Algernon” about a laboratory mouse named Algernon. The mouse undergoes a nootropic-esque surgical procedure that dramatically amplifies his intelligence. The experiment is deemed so successful, that scientists decide to test the procedure in a human character named Charlie Gordon. Prior to the artificial enhancement of Charlie’s …
Saphris (Asenapine) is an atypical antipsychotic medication that was approved in 2009 for the treatment of schizophrenia and bipolar disorder. It is a relatively new atypical antipsychotic, and is considered a chemical derivative of the tetracyclic antidepressant (TeCA) mianserin. It is manufactured in a sublingual format, which some may perceive as an upgraded or novel …
While people will always be in search of specific diets to help them lose weight, in recent years there is an increasing interest in how certain foods affect the human brain. It is estimated that there are currently over 5 million individuals in the United States that have been diagnosed with Alzheimer’s disease, and dietary …
It appears as though the pharmaceutical juggernaut Eli Lilly is facing major legal backlash for failure to disclose discontinuation effects associated with their medication Cymbalta (Duloxetine). Cymbalta is an SNRI antidepressant that was approved in August 2004 for the treatment of major depression. A woman named Claudia Herrera has been making news headlines because she …
Oxaloacetate (or Oxaloacetic Acid) is an organic compound that is involved in many neurophysiological processes within your body. It plays a key role in functions such as: amino acid synthesis, citric acid cycle, fatty acid synthesis, gluconeogenesis, glyoxylate cycle, and the urea cycle. For example, oxaloacetate is considered an intermediate in the Kreb’s cycle prior …