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Cannabidiol (CBD) Side Effects & Adverse Reactions

CBD (Cannabidiol) is a phytocannabinoid with medicinal properties derived from the cannabis plant (i.e. marijuana).  Of all ~113 active phytocannabinoids, or plant-based chemical constituents within the cannabis plant, cannabidiol is most abundant and accounts for approximately 40% of the plant’s extract.  Unlike other phytocannabinoids that induce intoxicating effects (e.g. THC or tetrahydrocannabinol), cannabidiol is devoid …

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Zoloft (Sertraline) & Headaches: Does It Cause or Treat Headaches?

Zoloft (Sertraline), is an SSRI (selective serotonin reuptake inhibitor) prescribed for the treatment of major depressive disorder, OCD (obsessive-compulsive disorder), panic disorder, and social anxiety disorder.  It was approved by the FDA in 1991 and initially marketed by the pharmaceutical company Pfizer.  In 2013, Zoloft became the single most popular antidepressant medication in the United …

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Humira (Adalimumab) & Weight Gain: A Common Reaction

Humira (Adalimumab) is a biologic, immunosuppressant medication sold and marketed by the pharmaceutical company AbbVie Inc.  More specifically, Humira functions as a TNF inhibitor whereby it binds to and blocks the physiologic effect of the proinflammatory cytokine known as “TNF-alpha.”  Blockade of inflammation induced by TNF-alpha makes Humira useful for the treatment of many autoimmune …

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Rexulti (Brexpiprazole) & Weight Gain: Will It Make You Fat?

Rexulti (Brexpiprazole), is an atypical antipsychotic that was jointly developed by pharmaceutical companies Otsuka and Lundbeck.  In 2015, the FDA approved Rexulti for the treatment of schizophrenia and major depressive disorder (as an adjunct).  Rexulti functions as a “serotonin-dopamine activity modulator” (SDAM) and is intended to be a superior successor to the antipsychotic Abilify (Aripiprazole) …

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Trintellix (Vortioxetine) & Weight Gain or Weight Loss?

Trintellix (Vortioxetine hydrobromide), formerly sold under the name Brintellix, is an antidepressant that was jointly developed by the pharmaceutical companies Lundbeck and Takeda.  In 2013, Trintellix received FDA approval for the treatment of major depressive disorder in the United States.  Trintellix is classified as a “serotonin modulator and stimulator” in that it functions as an …

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ZzzQuil Side Effects & Adverse Reactions (List)

ZzzQuil is an over-the-counter medication utilized most frequently to enhance sleep quality among individuals with allergies or the “common cold.”  However, because ZzzQuil is a potent sleep aid, individuals without health problems sometimes use the medication to help manage insomnia.  On occasion, ZzzQuil is even administered for the treatment of motion sickness and extrapyramidal symptoms …

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Rexulti Side Effects & Adverse Reactions (List)

Rexulti (Brexpiprazole), is an atypical antipsychotic approved by the FDA for the treatment of schizophrenia and major depressive disorder (as an adjunct).  The drug was engineered via collaboration between pharmaceutical companies Otsuka and Lundbeck and is considered the successor to Abilify (aripiprazole), a formerly top-selling antipsychotic medication with an expired patent.  Although Rexulti is marketed …

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