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Adjunct Celecoxib for Depression & Mania: Treatment with a COX-2 Inhibitor

Celecoxib, a selective COX-2 inhibitor, shows promise as an effective and safe adjunct treatment for major depression and mania, according to a new comprehensive systematic review. The analysis also found celecoxib improved symptoms when used as a standalone antidepressant in patients with somatic disorders. However, evidence for efficacy in bipolar depression remains unclear. Key Facts: …

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Are Binaural Beats & Brainwave Entrainment Effective? Latest Research (2023)

The phenomenon of binaural beats and their proposed ability to synchronize brainwave frequencies through a process called brainwave entrainment (BWE) has intrigued neuroscientists and the public for decades. However, the empirical evidence for BWE remains inconclusive. A recent systematic review evaluated 14 studies on binaural beats and EEG markers of brainwave entrainment, finding mixed results …

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Case Report: Depression Treated with Deep Brain Focused Ultrasound (2023)

Deep brain stimulation using focused ultrasound leads to rapid remission of severe depression in breakthrough patient case study. Key Facts: Focused ultrasound targeted and suppressed hyperactive areas linked to depression. Stimulation lasted just 64 minutes yet caused depression remission for over 6 weeks. Approach is noninvasive and precisely targeted with no side effects observed. Technology …

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Does MSG Cause Headaches? Monosodium Glutamate Research Reviewed

Monosodium glutamate (MSG), commonly used as a flavor enhancer, has been controversially linked to headaches for decades. Key Facts: Human studies linking MSG to headaches have inconsistent findings, especially when MSG is consumed with food. Studies in which MSG reportedly causes headaches often have methodological flaws like inadequate blinding due to MSG’s strong taste. MSG …

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