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Genetic Risk for Low Vitamin D Linked to Lower Social Motivation in First-Episode Psychosis (2024 Study)

Recent research reveals a notable association between vitamin D levels and the severity of negative symptoms in individuals with first-episode psychosis (FEP). A new study explored the genetic predisposition towards lower vitamin D levels and its impact on symptom severity in schizophrenia and related disorders. Highlights: Vitamin D & Psychosis Connection: Lower levels of vitamin …

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Genetics & Age-Related Cognitive Decline: Insights from TOMORROW Trial (2024 Study)

In a study utilizing data from the TOMMORROW trial, researchers have embarked on a novel exploration of genetic associations with cognitive change in older individuals. Employing a genome-wide association study (GWAS) approach, they’ve identified specific genetic variants linked to cognitive dynamics, providing new insights into the genetic underpinnings of cognitive change with aging. Highlights: Novel …

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Combo of Neuroimaging, Transcriptome, Epigenetics to Understand Gray Matter Abnormalities in Major Depression (2024 Study)

Major depressive disorder (MDD) affects millions worldwide, yet its underlying causes remain largely enigmatic. A new study integrated neuroimaging, transcriptomic, and epigenetic data to better understand the genetic underpinnings of MDD. This comprehensive approach revealed a complex interplay between brain structure, gene expression, and DNA methylation, offering new insights into this debilitating condition. Highlights: Integrative …

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