Mental Health DailyResearch. Evidence. Perspective.Published research on Genetics.
Schizophrenia’s genetic architecture sits awkwardly between neurons and the immune system. A 2026 CRISPR screen of 30 schizophrenia-associated genes in human microglia-like cells found that …
Read articleA 2026 Egyptian study of 76 children found a sharp mental-health gradient in phenylketonuria (PKU): late-diagnosed children had higher depression scores, lower quality of life, lower IQ, and…
Read articleA 2026 PRONIA preprint involving 727 discovery-sample participants found that early mental illness severity cut across psychosis risk, recent psychosis, and recent depression: groups with hi…
Read articleA 2026 mechanistic Alzheimer’s study found that suppressing NDST3 shifted lysosomal pH in APP695Swe neuronal cells from 5.6 back below 5.0, then reduced amyloid-β, MAPT/tau pathology, neuron…
Read articleA 2026 Cell & Bioscience study found that poly-GR, one of the toxic dipeptide-repeat proteins produced in C9orf72-linked amyotrophic lateral sclerosis (ALS), pushed motor neuron-like cells t…
Read articleA 2026 multi-ancestry genome-wide association study of urinary aMT6s, a melatonin metabolite used as a proxy for overnight melatonin secretion, found 0 genome-wide significant loci in 11,744…
Read articleA 2026 DIVERGE analysis of 3,677 antidepressant-exposed patients with major depressive disorder in Pakistan classified 34% as treatment resistant, while 86% received psychotropic polypharmac…
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