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Triple Reuptake Inhibitors For Depression: SNDRI Drugs Outlook

There is a newer class of antidepressant drugs called Triple Reuptake Inhibitors (TRI’s or SNDRI drugs) being developed that target all major neurotransmitters involved in depression: serotonin, norepinephrine, and dopamine. The thought process behind the creation of this new class of triple reuptake inhibitors is that they will target all three major neurotransmitters that are thought …

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Low Norepinephrine and Depression: Is There A Link?

Norepinephrine also sometimes referred to as “noradrenaline” works as both a hormone and neurotransmitter. It helps promote vigilant concentration and is different from dopamine in the fact that dopamine has a greater influence on cognition. When you become stressed, norepinephrine is secreted by the sympathetic nervous system which leads to an increased amount of heart …

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Do Antidepressants (SSRI’s) Lower Testosterone Levels?

Many people that take antidepressants, specifically SSRI’s (selective-serotonin reuptake inhibitors), find out that they have abnormally low testosterone. So what does this all mean? Did the initial low testosterone lead the individual to become depressed and go on an antidepressant? Or did the treatment with an antidepressant actually slowly reduce the individual’s natural ability to …

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Strattera (Atomoxetine) For Depression: Norepinephrine Reuptake Inhibitors

Strattera is an NRI or “norepinephrine reuptake inhibitor” meaning it prevents the reuptake of the neurotransmitter norepinephrine. This drug has been found clinically effective for treating cases of ADHD. Many doctors prefer to prescribe this drug over a potent stimulant like Adderall simply because it doesn’t have any major addictive properties or potential for abuse. …

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Cymbalta (Duloxetine) Withdrawal Symptoms + My Personal Experience

Cymbalta (Duloxetine) was officially approved by the FDA in 2004 as a new treatment for major depression. It is classified as an SNRI antidepressant which means it inhibits the reuptake of serotonin as well as norepinephrine. This medication was also devised to target more of the physical symptoms associated with depression and was approved by …

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Viibryd (Vilazodone) Withdrawal Symptoms: How Long Do They Last?

Viibryd (Vilazodone) is a relatively popular new antidepressant that has been found effective for treating symptoms of major depression. Many people have had success with this antidepressant and tend to not experience as many of the other side effects associated with most SSRI’s such as: weight gain and sexual dysfunction. Although this drug may be …

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Prozac (Fluoxetine) Withdrawal: Symptoms + Duration

Prozac (Fluoxetine) is among the most popular antidepressant medications on the market. It operates as an SSRI (selective-serotonin reuptake inhibitor) meaning it prevents the reuptake of the neurotransmitter serotonin. It is thought to help with both depression and anxiety, but it is also prescribed for a number of other conditions. Although most people end up …

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