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Triple Reuptake Inhibitors For Depression: SNDRI Drugs Outlook

There is a newer class of antidepressant drugs called Triple Reuptake Inhibitors (TRI’s or SNDRI drugs) being developed that target all major neurotransmitters involved in depression: serotonin, norepinephrine, and dopamine. The thought process behind the creation of this new class of triple reuptake inhibitors is that they will target all three major neurotransmitters that are thought …

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Low Norepinephrine and Depression: Is There A Link?

Norepinephrine also sometimes referred to as “noradrenaline” works as both a hormone and neurotransmitter. It helps promote vigilant concentration and is different from dopamine in the fact that dopamine has a greater influence on cognition. When you become stressed, norepinephrine is secreted by the sympathetic nervous system which leads to an increased amount of heart …

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