Rexulti (Brexpiprazole) is a drug that was approved July 10, 2015 for the treatment of schizophrenia and as an adjunctive option for major depressive disorder. In clinical trials it was referred to as the chemical “OPC-34712” and is being marketed as a superior successor to Abilify (Aripiprazole) due to the fact that Abilify’s patent expired …
Anyone living in a big city that has taken a vacation to experience nature (e.g. a cabin in the woods) can often detect a stark contrast in air quality. In the big city, the air you’re breathing in often smells dull and polluted, and you may sense that it’s taking a toll on your health. …
Depression is a growing epidemic that affects the lives of nearly 15 million Americans. The number of individuals diagnosed with depression will continue to grow as a result of population growth, poor diet, environmental toxins, genetic polymorphisms, and other unique neurophysiological factors. As a result of depression, it is estimated that nearly 1 out of …
A recent publication in the Journal of Psychiatric Practice documented that nearly 4/5 individuals diagnosed with major depression are considered ineligible to participate in clinical trials for new antidepressant drugs. This means that for every 5 individuals with depression that attempt to join an antidepressant clinical trial, only one will meet inclusion criteria for registration. …
We’ve all heard the media-driven dogma that everyone needs at least 8 hours of sleep per night for optimal neurophysiological performance. Striving for 8 hours of sleep is generally a healthy rule of thumb [for most people], but shouldn’t be considered a utopian amount for everyone. Many individuals diagnosed with major depressive disorder (MDD) sleep …
Brain imaging (neuroimaging) was invented in the 1880s by Angelo Mosso, who devised a technique referenced as the “human circulation balance.” This technique was able to assess how blood was redistributed throughout the brain as an individual experienced emotion and/or engaged in intellectual tasks. It wasn’t until the early 1900s that a newer, improved brain …
A ketogenic diet involves consumption of foods with high fat (80%), moderate protein (15%), and low carbohydrates (5%). Consistent intake of high fat, moderate protein foods, with simultaneous avoidance of carbohydrates, allows the body to transition from using glucose (sugar) as a primary source of fuel, to using ketone bodies (commonly called “ketones”). During ketosis, …