hit counter

tDCS Plus Cognitive Training Improved Cognition Short-Term by SMD 0.36

MHD featured image for tDCS plus cognitive training in cognitive impairment.

A 2026 medRxiv meta-analysis of 27 trials found that transcranial direct current stimulation added to cognitive training improved global cognition immediately after treatment by SMD 0.36 compared with cognitive training alone.1 The signal was small, short-term, and rated very low certainty, so it is not evidence that tDCS is a durable cognitive-rehabilitation shortcut. Research Highlights …

Read more

Post-Stroke Aphasia Theory of Mind Linked to Cerebral Microbleeds

MHD featured image for post-stroke aphasia, theory of mind, and cerebral microbleeds.

A 2026 medRxiv preprint involving 44 people with chronic post-stroke aphasia found reduced performance on nonverbal false-belief tasks in 23% of participants on the Reality-Unknown task and 36% on the Reality-Known task, with accuracy tied more clearly to cerebral microbleed burden than to aphasia severity.1 The result reframes social-cognitive testing after stroke as a vascular …

Read more

Depression SPECT Study Links Worry to NeuroMark Brain Networks

MHD featured image for NeuroMark SPECT and depression biomarkers.

A 2026 medRxiv preprint used 68 NeuroMark SPECT components to analyze 2,746 psychiatric patient scans and 76 controls, linking depression-related worry/rumination and social disinterest to brain-network patterns.1 This preprint is useful as a large biomarker-generating map, but the clinical-diagnostic claim needs much more caution than the sample size alone suggests. Research Highlights Large clinical SPECT …

Read more