Mental Health DailyResearch. Evidence. Perspective.Published research on hippocampus.
A 2026 Nature Communications mouse study tested 7,736 possible connections in the hippocampal CA3 memory circuit and found a developmental shift from dense early wiring toward sparse structu…
Read articleA 2026 systematic review argues that catatonia should be read as a limbic-cortical circuit syndrome, with motor shutdown tied to brain systems for threat, salience, motivation, and emotional…
Read articleA 2026 Nature single-neuron study recorded 3,109 medial temporal lobe neurons from 16 neurosurgical epilepsy patients and found that human item-context memory mostly used separate item and c…
Read articleA 2026 medRxiv preprint found that 26 autistic children performed similarly to 25 typically developing children on objective SPACE navigation tasks, contrary to the prediction, while autisti…
Read articleA 2026 mouse and cell study found that ATP11B loss pushed aged brains toward hippocampal iron accumulation, mitochondrial dysfunction, neuronal ferroptosis, and worse memory behavior than wi…
Read articleA 2026 multi-cohort Alzheimer’s disease study found that MRI radiomics from the hippocampus and amygdala linked plasma pTau217 and smell identification to cognitive impairment — with more ad…
Read articleA 2026 resting-state fMRI study of 800 adults found intra-thalamic hypoconnectivity across schizophrenia, bipolar disorder, and major depression, but schizophrenia showed far broader subcort…
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