MentalHealthDaily

SSRIs + DOACs: No Excess Bleeding vs. Other Antidepressants

by GLOOM

Stylized illustration of an SSRI capsule alongside a DOAC tablet against a vascular network background, representing the bleeding-interaction question in primary care.

SSRIs raise bleeding risk on their own. DOACs (direct oral anticoagulants — apixaban, rivaroxaban, dabigatran, edoxaban) raise it more. The intuitive worry is that combining them stacks the two effects. A new BJGP Open analysis from Chau and colleagues argues the stacking is smaller than most popular framings claim, and that the real safety question …

Lithium in Pregnancy: Why Late Discontinuation Backfires

by GLOOM

Photoreal illustration representing lithium prescribing decisions during pregnancy, with imagery of a pregnant figure and pharmaceutical motifs.

Lithium prescribing during pregnancy sits in a knot of competing risks. The teratogenicity data have been recalibrated dramatically since the 1970s, while the postpartum-relapse data have moved in the opposite direction. Most popular framing still treats lithium as a uniquely dangerous fetal exposure to be avoided when possible. The new Chauhan UK cohort shows what …