A 2026 SEEearly baseline report found that 53.3% of 184 young people with early schizophrenia-spectrum psychosis were not in employment, education, or training at study entry, even though 97.8% had at least a lower- or upper-secondary school-leaving qualification.1 Psychosis had already interrupted the bridge from school into training, college, or competitive work. Research Highlights NEET …
A 2026 first-in-human medRxiv preprint reported that closed-loop subgaleal intersectional short-pulse stimulation shortened stimulated seizures by 52% on average and reduced seizure incidence by 80.9% after 48 hours in 5 high-frequency therapy-resistant epilepsy patients. The signal is promising because it combines responsive seizure detection with electrode strips placed under the scalp rather than electrodes implanted …
A 2026 participatory-design and case-study paper turned smartphone mental-health data into 6 clinician-facing visualizations for an 8-week anxiety/depression digital clinic, using feedback from 15 clinicians and 3 clinical supervisors. The useful claim is workflow-level: charts made passive sensing and symptom ratings discussable inside care, but the paper did not test whether the visualizations improved clinical …
A 2026 Australian interview study involving 27 adults with methamphetamine use problems found that 21 participants, or 77.8%, had never previously sought treatment for methamphetamine use. Research Highlights Most had never sought treatment: Peart et al. interviewed 27 adults and found that 77.8% had not previously sought methamphetamine treatment before entering the parent trial.1 3 …
A 2026 systematic review of subcallosal cingulate (SCC) functional connectivity found 28 qualifying resting-state fMRI studies in depression: 21 rTMS/iTBS studies, 4 ECT studies, 3 focused-ultrasound studies, and 0 DBS or tDCS studies.1 That number is the useful correction: SCC DBS may still be biologically plausible, but the current fMRI connectivity literature mostly explains noninvasive …
Auditory targeted memory reactivation during a 2-hour nap did not improve motor retention in 20 Parkinson’s disease patients or 20 healthy older adults, even though the same cues changed sleep physiology by reducing spindle density and increasing slow-wave density.1 Research Highlights First Parkinson’s TMR test: Micca et al. studied 20 Parkinson’s disease patients and 20 …
A 2026 meta-analysis of 56 controlled trials found the clearest gamma-frequency neuromodulation signal in schizophrenia: overall symptoms improved vs. control (g = −0.46), global cognition improved (g = 0.55), and MDD showed a smaller depression effect than the schizophrenia symptom estimate (g = −0.34). Bipolar disorder and autism stayed directional but nonsignificant, and the paper’s …