Mental Health DailyResearch. Evidence. Perspective.Published research on longitudinal cohort.
In 17,972 US adults followed for up to 22 years, starting to volunteer was linked to slower cognitive decline associated with the APOE e4 Alzheimer's gene variant, with the clearest link at …
Read articleDementia rates in the US, UK, Netherlands, Sweden, France, and several other high-income countries have been falling for decades, despite population aging. The standard explanation — improve…
Read articleA 2026 UK Biobank analysis by Aas et al. in BMC Medicine tests the “adversity leaves a fixed biological scar” framing against five biological aging markers in 153,557 middle-aged and older a…
Read articleA 2025 longitudinal analysis of 1,528 older Chinese Americans by Chen et al. in the Journal of Prevention of Alzheimer’s Disease says something more specific than “stress causes Alzheimer’s”…
Read articleA 2026 PPMI analysis found that Parkinson’s patients with positive CSF α-synuclein seed amplification assay results kept gaining levodopa benefit over follow-up, while SAA-negative patients …
Read articleA 2026 ALSPAC analysis tested a narrow claim behind routine genetic screening for childhood attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD): whether rare c…
Read articleUntil recently, Alzheimer’s pathology could only be confirmed in living patients via PET imaging or lumbar puncture. Plasma p-tau217 changed that calculus — but how to interpret a positive r…
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