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A 2025 paper by Gu et al. in Molecular Psychiatry — the largest study of its kind — finds that higher common-variant genetic risk for autism predicts lower cortical neurite density in 31,748…
Read articleA 2026 study by Bai et al. in Dialogues in Clinical Neuroscience uses Mendelian randomization (MR) — inherited genetic variants as a natural experiment to test causality — and concludes that…
Read articleA 2026 Parkinson’s disease study used gene-expression data and genome-scale metabolic modeling to predict patient-level metabolite patterns, then separated 104 patients into 3 metabolic subg…
Read articleAn Ethiopian umbrella review estimated perinatal depressive symptoms at 22.49% across 8 systematic reviews and meta-analyses. Antenatal and postnatal rates were similar, so the burden spans …
Read articleA Global Burden of Disease analysis estimated that U.S. age-standardized substance-use disorder disability-adjusted life-year rates rose 213.5% from 1990 to 2019, with opioid use disorders p…
Read articleA 2026 review argued that G protein-coupled receptor 30 may connect estrogen signaling, trigeminal pain pathways, and migraine biology, but migraine-specific human trials of GPR30-targeted d…
Read articleA 2026 mouse and cell study found that ATP11B loss pushed aged brains toward hippocampal iron accumulation, mitochondrial dysfunction, neuronal ferroptosis, and worse memory behavior than wi…
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