Mental Health DailyResearch. Evidence. Perspective.Published research on Drugs.
A 2026 German-Austrian cohort analysis found that people with schizophrenia who were taking quetiapine scored modestly higher on demanding working-memory tests than sex- and age-matched pati…
Read articleA 2026 umbrella review of 16 systematic reviews covering 371 trials found strong medication evidence for tobacco and opioid use disorders, modest benefits for alcohol use disorder, and no ap…
Read articleA 2026 analysis of 41 randomized studies involving 21,025 adults with schizophrenia found the largest estimated reductions in hostility and aggression for clozapine (standardized mean differ…
Read articleA 7-trial review favored adding celecoxib to antidepressants for depression, but its benefit was not confirmed after 3 high-risk trials were excluded.
Read articleA 2026 ANTLER mechanistic analysis found no evidence that maintaining antidepressants preserved a happier facial-emotion recognition pattern compared with placebo substitution at 12 weeks (a…
Read articleA 2026 case report described valproate 800 mg/day improving agitation in residual-phase treatment-resistant schizophrenia but being followed by hypoglycemia and pancytopenia; after discontin…
Read articleA zebrafish experiment found that one 1-hour ayahuasca exposure reversed several effects of 14 days of unpredictable chronic stress: impaired sociability, anxiety-like behavior, stress-relat…
Read article
