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NSI-189 For Depression: New Drug Grows Hippocampus

Individuals diagnosed with major depression often are found to have reduced volume within their hippocampus. The hippocampus is a small region of the brain that is responsible for regulating various memory and spatial navigation functions. It is also believed to play a pivotal role in the regulation of mood. Modern day antidepressants such as SSRIs …

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2 New Kappa Opioid Receptor (KOR) Antagonists For Depression

The quest to come up with a superior antidepressant is in full effect among biotech and pharmaceutical companies. Although there are some companies that are still tweaking various formulations of serotonergic, noradrenergic, and dopaminergic substances (e.g. triple reuptake inhibitors) others are thinking outside the box. Based on current trends, the next decade or two of …

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New Antidepressant GLYX-13 (Clinical Trials): Partial NMDA Receptor Agonist

A new antidepressant chemically named “GLYX-13” was developed by the biotech company Naurex for individuals with treatment-resistant depression. It is currently in clinical trials as an antidepressant augmentation strategy, meaning it is used as an add-on to already approved treatments. However, most evidence would suggest that it works extremely well as a standalone treatment option. …

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How To Improve Psychiatric Treatment Outcomes with Technology & Variable Tracking

It’s blatantly obvious that psychiatry is an imperfect practice. These days people often seek the help of a psychiatrist with the belief that a pill can be prescribed to essentially cure a disease or get symptoms of a mental illness under control. While psychiatry can offer many benefits in the treatment of certain conditions, especially …

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Antidepressant Roulette: Switching / Trying New Medications Is Often Problematic

Many people seek out treatment for their depression from general practitioners and psychiatrists. If you have a serious mental illness that requires pharmaceutical treatment, it is generally best to work with a quality psychiatrist. Regardless of whether you seek the help of a psychiatrist or simply go to your family doctor, finding the right antidepressant …

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