Mental Health DailyResearch. Evidence. Perspective.Published research on Depression.
A 2026 analysis followed 161 people with cancer for 9 months to evaluate whether 2 forms of online mindfulness-based cognitive therapy reduced psychological distress: therapist-led group-ble…
Read articleA 2026 preclinical study found that 25C-NBF, a selective 5-HT2A psychedelic phenethylamine, increased plasticity-related markers and produced rapid antidepressant-like effects in male rodent…
Read articleA 2026 review in Purinergic Signalling argues that P2X7 receptors are one of the clearest molecular bridges between stress, ATP danger signaling, microglial inflammation, NLRP3 inflammasome …
Read articleA 2026 systematic review found that microglia-related immune signals do not line up cleanly with psychiatric diagnosis labels: major depression showed frontolimbic TSPO-PET increases, while …
Read articleIn a 2,411-person multinational twin-consortium study, depressive symptoms increased significantly as death approached. The strongest design check compared twins directly: twins who died had…
Read articleA 2026 structural MRI study found that cerebellar gray-matter patterns helped distinguish first-episode bipolar depression from unipolar depression: a model using significant cerebellar lobu…
Read articleA 2026 Communications Biology rat study found that enriched housing reversed early-life-stress visceral hypersensitivity and depression-like behavior by normalizing a CB1 receptor-linked pre…
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