Mental Health DailyResearch. Evidence. Perspective.Published research on Depression.
A 147-person feasibility randomized trial found that both a structured AI therapy chatbot and general ChatGPT reduced PHQ-9 depression scores compared with assessment-only control, with effe…
Read articleA 2025 Journal of the American Chemical Society study identified 4 unusual Morganella morganii phospholipids that activated TLR2/TLR1 immune receptors and induced inflammatory cytokines, esp…
Read articleMajor upper-extremity amputation was linked to substantially higher odds of new mental-health diagnosis, antidepressant initiation, and psychotherapy claims than minor upper-extremity amputa…
Read articleA 2026 biomarker study found kynurenine-pathway activation in inflammatory major depressive disorder (MDD), but not across all depression cases. Compared with non-inflammatory MDD and health…
Read articleLow-burden digital phenotyping is appealing because college students already leave daily traces in phones, messages, sleep logs, and voice samples. In Henry et al.’s 120-student study, posit…
Read articleA 2026 NHANES analysis of 6,502 adults found that urinary 3-PBA, a pyrethroid insecticide metabolite, was modestly associated with depression risk at OR = 1.02 per 1 μg/L, while self-reporte…
Read articleA 2026 case series of 5 adults with bodily distress disorder found mean pain scores decreased from 9.0 to 3.8 after accelerated transcranial direct current stimulation, with 4 of 5 patients …
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