A 2026 UK Biobank analysis by Aas et al. in BMC Medicine tests the “adversity leaves a fixed biological scar” framing against five biological aging markers in 153,557 middle-aged and older adults — and the marker that moves most reliably isn’t telomere length or any metabolomic clock.1 Research Highlights 153,557-participant test: Aas et al. measured …
A 2026 medRxiv preprint found that 26 autistic children performed similarly to 25 typically developing children on objective SPACE navigation tasks, contrary to the prediction, while autistic children rated their own navigation ability lower on the Santa Barbara Sense of Direction scale.1 Research Highlights Objective performance did not separate groups: 26 autistic children and 25 …
A 2026 Human Connectome Project MRI study linked asymmetric anterior cingulate cortex sulcal pattern to lower delay discounting in 390 healthy young adults: asymmetric ACC morphology predicted a higher delay-discounting area under the curve, meaning delayed rewards lost less value.1 The finding is not a diagnostic scan for impulsivity, but it puts an early-formed cortical-folding …
A 2026 community study of 101 older adults found that pulse-wave harmonics changed in a more organized way during a subtraction task in cognitively intact participants than in people with MoCA-defined mild cognitive impairment: amplitude-coherence scores averaged 9.00 vs. 6.40, a 2.60-point gap on a 0-10 scale. Research Highlights Cognitive stress exposed the signal: resting …
A 2026 ABCD stop-signal fMRI study found that group-level cognitive-control brain signals often failed to describe within-person brain dynamics: across 16 comparisons, between-person and within-person associations diverged, and several reversed direction.1 The practical warning is narrow but sharp: a brain pattern that separates people in a group may be the wrong map for explaining how …
A 2026 TADPOLE modeling study reported that a sequential neural process with normalizing flows predicted future Alzheimer diagnostic stage with mAUC 0.965 ± 0.006, ahead of the authors’ earlier sequential-neural-process model at 0.937 ± 0.014.1 The result is a strong benchmark signal for uncertainty-aware disease-progression AI, but it is still retrospective modeling evidence rather than …
A 2026 study by Bai et al. in Dialogues in Clinical Neuroscience uses Mendelian randomization (MR) — inherited genetic variants as a natural experiment to test causality — and concludes that migraines causally lower cognitive performance in a Han Chinese sample.1 The headline conclusion is plausible; the effect-size numbers in the popular MR shorthand (odds …