Mental Health DailyResearch. Evidence. Perspective.Published research on prefrontal cortex.
Neurons that tracked a remembered smell turned up all over the mouse brain in a newly released dataset of 33,028 neurons recorded from 40 mice. The 2026 data paper makes those recordings fre…
Read articleGuanfacine, a non-stimulant ADHD medication, reduced hyperactivity in autistic children in a placebo-controlled trial. A 2026 review argues it may also steady prefrontal brain signaling and …
Read articleThe textbook story of social anxiety disorder is broken amygdala-prefrontal regulation — an overactive threat system the prefrontal cortex can’t calm down. A 2026 effective-connectivity stud…
Read articleA 53-study resting-state functional magnetic resonance imaging (fMRI) meta-analysis found substance use disorder (SUD) linked to altered connectivity across prefrontal, striatal, thalamic, c…
Read articleA 97-dyad adolescent fMRI study found that trauma-exposed youth with high posttraumatic stress symptoms did not use parent-observed safety learning in the usual way: their arousal rose to a …
Read articleA 2026 multimodal MRI analysis of 509 healthy adults found that fear acquisition, extinction learning, and renewal were not predicted by one generic “fear circuit” score: functional connecti…
Read articleAlcohol’s effects on the brain, especially among the elderly, have long been a subject of scientific inquiry. A recent study from Gothenburg, Sweden, provides new insights into how varying l…
Read article
