Mirapex (Pramipexole) is a drug that is approved by the FDA for the treatment of Parkinson’s disease and RLS (restless leg syndrome). Classified as a dopamine receptor agonist, pramipexole elicits partial or full agonism upon D3 receptors, D2 receptors (2L/2S), and D4 receptors. Interestingly, pramipexole also appears to modify mitochondrial function, and to a negligible …
Mirapex (Pramipexole) is a medication that was approved by the FDA in 1997 for the treatment of idiopathic (early-stage and advanced) Parkinson’s disease. Analysis of the drug’s pharmacodynamics reveals its function as a mixed partial/full dopamine agonist, with highest affinity for: D3 receptors, D2 receptors (D2S and D2L), and D4 receptors (in that order). To …
We all know that getting enough sleep promotes healthy brain function and optimal cognitive performance. Most sources recommend getting approximately 8 hours of sleep per night, but the amount of sleep it takes for you to feel refreshed should be individualized. Someone who is training for a marathon will generally need more sleep (over 8 …
While people will always be in search of specific diets to help them lose weight, in recent years there is an increasing interest in how certain foods affect the human brain. It is estimated that there are currently over 5 million individuals in the United States that have been diagnosed with Alzheimer’s disease, and dietary …
Anyone living in a big city that has taken a vacation to experience nature (e.g. a cabin in the woods) can often detect a stark contrast in air quality. In the big city, the air you’re breathing in often smells dull and polluted, and you may sense that it’s taking a toll on your health. …
Namenda (Memantine) is a drug that was approved by the FDA in 2003 for the treatment of Alzheimer’s disease. Research suggests that Namenda has a small effect in reducing symptoms among those diagnosed with moderate or severe cases of Alzheimer’s. It appears to have no significant effect when administered to individuals diagnosed with milder cases …
In recent years, increasing evidence has suggested that certain types of commonly prescribed medications may cause increased risk of developing dementia. This ranges from drugs used to treat anxiety (e.g. Xanax) to over-the-counter drugs (e.g. Benadryl). A majority of these medications tend to depress activity in the CNS and help minimize arousal and/or anxiety. Dementia …