Mental Health DailyResearch. Evidence. Perspective.Published research on Depression.
In a 2026 mouse study, a single 10 mg/kg dose of ketamine reduced swim immobility in stressed mice with the circuit intact (7 mice, P = 0.0093) but did nothing when the thalamic nucleus reun…
Read articleIn a brain-scan study of 135 young adults, higher depression and social anxiety symptoms were linked to giving up rewards to avoid demanding judges, with a stronger threat response and weake…
Read articleIn 7,952 US adults from NHANES 2017-2023, depression was linked to 61% higher odds of a gallstone diagnosis and severe depression to 2.4 times the odds, but the link weakened and lost signif…
Read articleIn 4,945 U.S. adults with asthma, depressive symptoms were linked to about 10 fewer months of survival over 15 years and a 41% higher adjusted death risk. Lower income accounted for about a …
Read articleIn 148 stroke patients with depression, slow and normal CYP2C19 metabolizers had similar escitalopram response and remission after 8 weeks. Stroke disability predicted outcomes better than g…
Read articleIn 447,821 UK Biobank adults, those who recalled being thinner than average at age 10 and had a high adult BMI had the highest rates of later depression and anxiety.
Read articleIn a 2026 study of 40 male rats under 6 weeks of daily restraint stress, 2 weeks of celecoxib improved open-field, maze and swim-test behavior and lowered hippocampal TNF-alpha, IL-1beta, IL…
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