Mental Health DailyResearch. Evidence. Perspective.Published research on TNF-alpha.
University students with subthreshold depression, meaning real depressive symptoms that fall short of a major depression diagnosis, had stronger connections in 3 cingulate brain circuits and…
Read articleA 2026 controlled study of 96 people found severe long-COVID fatigue across 3 validated fatigue scales, but the tested peripheral inflammation, cellular-stress, neuroprotection, and autoimmu…
Read articleA 210-person randomized assessor-blinded trial found that adding weekly Hegu-point catgut embedding to gabapentin improved 4-week postherpetic-neuralgia response from 80.00% to 92.38%; compa…
Read articleA 2026 case-control study found that treatment-naive adults with attention-deficit/hyperactivity disorder (ADHD) had much lower serum SIRT-1, Nrf-2, and HO-1 than matched controls, while TNF…
Read articleThe broad cytokine story failed its most direct community test: in 972 adults, depression, alcohol use, and alcohol use disorder (AUD) were not associated with C-reactive protein (CRP) or a …
Read article‘Depression is inflammation’ holds for a subgroup of patients, not for everyone. Community-sample and twin data weaken the broader version of the claim.
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