How Much Does Loneliness Raise Dementia and Suicide Risk?
Loneliness raises measured risk of Alzheimer’s, suicidal ideation, and completed suicide. The associations are documented; the precise magnitudes are not.
Read articleDepression
Published research on Depression.
When Inflammation Drives Depression — and When It Doesn’t
‘Depression is inflammation’ holds for a subgroup of patients, not for everyone. Community-sample and twin data weaken the broader version of the claim.
Read article
ECT: A Modern Reappraisal of Suicide, Dementia, and Mortality
Modern administrative cohorts find no dementia signal for ECT and link it to lower suicide and mortality. The supportive literature carries known biases worth flagging.
Read article
Exercise for Depression and Anxiety: 2025 Evidence Synthesis
Exercise reliably reduces depression and anxiety symptoms — but the cardio-vs-resistance gap and antidepressant parity claims are overstated.
Read article
Sex Differences of Gut Bacteria (Microbiome) in Major Depression (2024 Review)
The intricate relationship between the gut microbiome and major depressive disorder (MDD) is gaining significant attention within the scientific community. Emerging research highlights sex-s…
Read article
Genetics of Major Depression Linked to Increased Risk of Obstructive Sleep Apnea (OSA) (2024 Study)
In a new study leveraging Mendelian Randomization, researchers highlight the complex interplay between psychiatric disorders, specifically major depressive disorder (MDD), and obstructive sl…
Read article
Hikikomori & Loneliness in Japan: Trends, Definitions, Demographics (2024 Report)
In Japan, a country facing unique demographic challenges, loneliness has emerged as a pressing public health issue, intricately linked with the phenomenon known as hikikomori, or extreme soc…
Read article