MentalHealthDaily

Teenage Cannabis Use vs. Cognition and Brain Development: THC vs. CBD (Toxicology Data)

by GLOOM

Photoreal illustration of an adolescent brain with overlay of cannabis molecules and cognitive metrics, conveying developmental neurocognitive impact.

Studies of adolescent cannabis effects on cognition have been limited by self-report and confounding. A 2026 longitudinal study by Wade and colleagues uses the Adolescent Brain Cognitive Development (ABCD) cohort with both self-report and biological toxicology, separating THC and CBD effects on developing cognition.1 Research Highlights Adolescence is a critical window for cognitive maturation, with …

Inflammation Tracks White-Matter MRI in Aging Adults

by GLOOM

Chronic low-grade inflammation rises with age, and a growing body of work asks whether peripheral inflammatory markers in blood track subtle changes in brain white-matter microstructure on MRI. A 2026 preprint from the Healthy Minds for Life cohort by Mishra and colleagues at Johns Hopkins examined 457 dementia-free adults aged 50–79 and found that higher …

Parental Mental Illness and Offspring IQ: Schizophrenia Hits Hardest

by GLOOM

Stylized illustration of cognitive trajectories in children of parents with severe mental illness, suggesting a gradient of effect across schizophrenia, bipolar disorder, and major depressive disorder.

A 1.6M-participant meta-analysis shows a clear gradient: parental schizophrenia hits offspring cognition harder than bipolar, which hits harder than MDD.

How Much Does Loneliness Raise Dementia and Suicide Risk?

by GLOOM

Stylized illustration representing the link between persistent loneliness and downstream cognitive and suicide-spectrum risks.

Loneliness raises measured risk of Alzheimer’s, suicidal ideation, and completed suicide. The associations are documented; the precise magnitudes are not.

Cognitive Function Does Not Predict Response to tDCS for Depression (2023 Trial)

by GLOOM

Transcranial Direct Current Stimulation (tDCS) has been explored as a potential treatment for major depressive disorder (MDD), particularly for patients who have not responded to traditional treatments like selective serotonin reuptake inhibitors (SSRIs). This non-invasive technique involves applying a weak electrical current to the prefrontal cortex of the brain, aiming to modulate neurocognitive functions. However, …

Myo-Inositol for Traumatic Brain Injury (TBI): Targeting BATF2 for Epigenetic & Transcriptomic Changes (2024 Study)

by GLOOM

Traumatic brain injury (TBI) remains one of the most challenging conditions for modern neurology, carrying a wide range of long-term consequences that can significantly impair an individual’s quality of life. In a new study, researchers analyzed the epigenetic landscape post-TBI, revealing significant DNA methylation changes in the hippocampus—a crucial area for memory and learning. The …

Effect of A Short Nap on Cognitive Function & Brain Connectivity with Sleep Deprivation (2023 Study)

by GLOOM

Sleep deprivation (SD) is a common issue in today’s fast-paced world, leading to temporary cognitive impairments that can significantly affect daily functioning. However, new research reveals that even a short nap following a period of SD can help reverse these impairments to some extent, shedding light on the brain’s remarkable ability to recover. Highlights: Cognitive …