hit counter

Autoimmune Focal Epilepsy: Antibody Testing and Immunotherapy

MHD featured image for autoimmune drug-resistant focal epilepsy and immunotherapy.

A 2026 structured review of autoimmune drug-resistant focal epilepsy argues for a narrow but clinically important claim: immune mechanisms can make seizures refractory in selected patients, but the evidence supports targeted testing and immunotherapy triage rather than treating every medication-resistant seizure disorder as autoimmune. Research Highlights Autoimmune epilepsy is a subset: Kunecki et al. estimated …

Read more

Prostate Cancer Survivors Who Smoke Showed Lower Verbal Memory Scores

MHD featured image for smoking, verbal memory, and cognition in prostate cancer survivors.

A 2026 study involving 118 prostate cancer survivors found the clearest lifestyle-cognition signal around smoking: smokers learned fewer words across repeated verbal-memory trials, while obesity and physical activity produced narrower reaction-time findings and no significant anxiety or depression differences. Research Highlights Smoking tracked verbal learning: in 118 prostate cancer survivors, smokers scored lower on Verbal …

Read more

Multiple Sclerosis Iron MRI Linked to Cognitive Impairment in 12 Studies

MHD featured image for multiple sclerosis, iron-sensitive MRI, and cognitive impairment.

A 2026 systematic review of advanced neuroimaging in multiple sclerosis narrowed 600 database records to 12 studies and found the clearest cognition signal in basal ganglia iron-sensitive MRI measures, while thalamic susceptibility was more variable and often tangled with atrophy. Research Highlights Basal ganglia signal was strongest: across 12 studies, elevated susceptibility or iron-related metrics …

Read more

Tau Oligomers Disrupted Nuclear Lamina in Alzheimer’s Disease Models

MHD featured image for tau oligomers, nuclear lamina disruption, and Alzheimer's disease models.

A 2026 Acta Neuropathologica study found that oligomeric tau was linked to early nuclear lamina disruption in Alzheimer’s disease tissue, PS19 tauopathy mice, and human induced pluripotent stem cell (iPSC)-derived neurons.1 The strongest claim is mechanistic: tau oligomers appeared to deform the nuclear envelope and disturb chromatin before overt neurodegeneration, but the work does not …

Read more

Neck-to-Height Ratio Screens Pediatric Sleep Apnea Better Than BMI

Editorial medical card showing pediatric sleep apnea screening with neck measurement, PSG waveforms, and airway anatomy.

A 2026 polysomnography study involving 685 children found that neck-to-height ratio identified moderate/severe pediatric obstructive sleep apnea better than BMI Z-score, waist-to-height ratio, or hip-to-height ratio. The signal was useful but not diagnostic: neck-to-height ratio reached AUC 0.781 overall, which is strong enough for triage but not strong enough to replace a sleep study.1 Research …

Read more

Alzheimer’s AI MRI Diagnosis: ANA-GNN Reaches 85.23% Accuracy in ADNI

MHD featured image for ANA-GNN Alzheimer's AI MRI diagnosis in the ADNI cohort.

A 2026 ADNI study reported 85.23% accuracy for ANA-GNN, a graph neural network that combined structural MRI regional features with clinical variables to classify cognitively normal controls, mild cognitive impairment, and Alzheimer’s disease.1 The result is useful, but the clinical-feature ablation dropped accuracy to 68.35%, so the model should be read as multimodal decision-support research, …

Read more

Gabapentin Plus Hegu Embedding: 92% Postherpetic Neuralgia Response

MHD featured image for gabapentin, Hegu catgut embedding, postherpetic neuralgia, and sleep quality.

A 210-person randomized assessor-blinded trial found that adding weekly Hegu-point catgut embedding to gabapentin improved 4-week postherpetic-neuralgia response from 80.00% to 92.38%; compared with gabapentin alone, the add-on arm also ended with lower sleep-problem scores and fewer adverse events.[1] This 2026 trial supports an add-on signal that still needs sham-controlled confirmation because follow-up lasted only …

Read more