The dopamine hypothesis of schizophrenia is the field’s longest-running mechanistic story, and most of its supporting evidence has been cross-sectional. A 2026 longitudinal PET study by Schulz and colleagues followed the same 28 patients across psychosis and early remission.1 Research Highlights The dopamine hypothesis of schizophrenia is the field’s longest-running mechanistic story. Cross-sectional 18F-DOPA PET …
Black Americans are diagnosed with schizophrenia-spectrum disorders at 2.42 times the rate of White Americans, and they also score higher on negative-symptom measures than White patients carrying the same diagnosis.2 A 2026 paper by Spann and colleagues asks why. Research Highlights Black Americans are diagnosed with schizophrenia-spectrum disorders at 2.42x the rate of White Americans, …
“Schizophrenia ages you faster” is the headline that gets repeated whenever a new biomarker study lands. The 2026 Fernandez-Egea, Garcia-Rizo and Kirkpatrick review — covering 170 studies across mortality, brain imaging, telomeres, epigenetic clocks, and metabolic markers — pushes back on that framing.2 The aging signal is genuine. “Accelerated” is the part that overshoots for …
A 1.6M-participant meta-analysis shows a clear gradient: parental schizophrenia hits offspring cognition harder than bipolar, which hits harder than MDD.
CBD has solid evidence for rare pediatric epilepsies, preliminary signal in anxiety and psychosis, and insufficient evidence for most conditions it’s marketed for.
AVATAR therapy ties CBT at end of treatment, edges ahead at 3-month follow-up, and uses half the sessions. The ‘better than CBT’ framing outpaces the formal statistics.
The intricate dance between parasites, mental health, and stress hormones is a subject of growing scientific inquiry, offering fascinating insights into how microscopic organisms might influence human behavior and psychiatric conditions. A recent study delves into the relationship between Toxoplasma gondii (TG), a common protozoan parasite, and its potential impact on individuals with schizophrenia, focusing …