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Neighborhood Deprivation Linked to Faster Epigenetic Aging in 370 Adults

Editorial card showing neighborhood deprivation, lifetime adversity, and epigenetic clock acceleration.

A 2026 medRxiv preprint involving 370 healthy adults found that each increase in neighborhood-deprivation percentile rank was associated with epigenetic age acceleration on 3 of 4 second-generation DNA-methylation clocks, with lifetime adversity explaining 20.3% of the GrimAge association and 23.3% of the PCGrimAge association.1 Research Highlights 3 of 4 clocks accelerated: each increase in Area …

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Teen Substance Use in South Africa: 30-Study Meta-Analysis

A 2026 PRISMA-compliant systematic review and meta-analysis in Drug and Alcohol Review consolidated 30 publications covering 202 prevalence estimates from 120,041 South African adolescents: pooled lifetime prevalence was 35.09% for alcohol use, 25.47% for tobacco use, and 10.47% for cannabis use.1 Research Highlights 30 publications, 202 estimates: pooled data covered 120,041 South African adolescents. Alcohol …

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Iceland Psychiatric Data: 21% Diagnosed, 34% on Psychotropics (2026)

MHD featured image for Iceland Psychiatric Health: 21% Diagnosed, 34% on Psychotropics.

Iceland is a registry-rich country with a small enough population that genuinely nationwide health data is feasible — not the survey-based approximations that anchor most psychiatric epidemiology elsewhere. A 2026 PLOS One study used the Iceland Screens, Treats, or Prevents Multiple Myeloma (iStopMM) cohort — 80,759 adults aged 40+, representing 54% of all eligible Icelanders …

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