A 2026 ALSPAC analysis tested a narrow claim behind routine genetic screening for childhood attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD): whether rare copy number variants (CNVs; deleted or duplicated DNA segments) make young-adult outcomes worse than ADHD/ASD status alone would predict. In 8,414 people with usable CNV data, ADHD and ASD predicted worse …
A 2026 case report linked 1 mg nightly guanfacine modified-release to first-ever cessation of intrusive deliberate self-harm thoughts in a 16-year-old with attention-deficit/hyperactivity disorder (ADHD), autism spectrum disorder (ASD) traits, borderline personality disorder (BPD) traits, and post-traumatic stress disorder (PTSD). The same case became more interesting after the patient stopped taking guanfacine and the self-harm …
Children with intellectual disability are 3–4x more likely to have a comorbid psychiatric disorder than peers without ID. A 2026 nationwide Korean study by Joo and colleagues tracks how those rates changed across a decade.1 Research Highlights Korean children and adolescents (ages 2–18) with intellectual disability had ADHD comorbidity rise from 30.2% in 2012 to …
Air pollution is a global concern with far-reaching impacts on human health, including its potential role in the development of Autism Spectrum Disorder (ASD). Recent studies, including Mendelian randomization analyses, provide compelling evidence that particulate matter, specifically PM2.5, may increase the risk of ASD, offering new insights into the environmental factors contributing to the condition. …
Attention Deficit Hyperactivity Disorder (ADHD) is a complex neurodevelopmental condition that significantly impacts individuals’ lives. Recent advancements in genetic research, particularly Mendelian Randomization (MR) studies, have begun to unravel the intricate genetic associations between ADHD and other psychiatric disorders, offering new insights into their comorbidities. By leveraging data from genome-wide association studies (GWAS), this research …
In the intricate puzzle of autism spectrum disorders (ASD), emerging research highlights a fascinating piece: the role of adiponectin, an anti-inflammatory adipokine, in the development and severity of ASD in children. With the backdrop of increasing ASD prevalence and the quest for biomarkers for early identification, the exploration of adiponectin offers a promising avenue for …
Recent research has shed light on the complex relationship between Autism Spectrum Disorder (ASD) and alterations in the cortical surface area (SA) of the brain. By analyzing large-scale genetic data, scientists have begun to unravel the intricate genetic correlations and causal connections between these two factors. Highlights: Genetic Correlation Identified: The study found a nominal …