Mental Health DailyResearch. Evidence. Perspective.Published research on ALS.
A 2026 Glia analysis found a shared microglial transcriptional program across 5 neurodegenerative contexts: ALS, frontotemporal dementia, Alzheimer’s disease, aging, and Parkinson’s disease.…
Read articleA Cell Reports study tied C9orf72-related ALS/FTD inflammation to a gut-bacterial product: inflammatory microbial glycogen appeared in 15 of 22 ALS fecal samples, 1 of 1 C9orf72-frontotempor…
Read articleA 2026 AB10015 post-hoc preprint reported 42.3% 5-year survival from amyotrophic lateral sclerosis symptom onset among patients originally assigned to masitinib 4.5 mg/kg/day with riluzole. …
Read articleA 2026 medRxiv preprint found that a training-free speech biomarker tracked dysarthria severity across 890 speakers, 10 corpora, and 5 full-pipeline languages, with all 5 consonant d-prime f…
Read articleA 2026 PRO-ACT analysis of amyotrophic lateral sclerosis (ALS) trial data found a signal that ordinary ALSFRS total-score slopes cannot even express: Shannon entropy trajectories diverged be…
Read articleA 2026 Australian ecological model found that 20-year-lagged cumulative population blood-lead burden was nonlinearly tied to motor neuron disease mortality (lead spline p = 0.00024), while n…
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