A 2026 medRxiv preprint found that 10 severe obsessive-compulsive disorder patients treated with anterior-limb-of-internal-capsule DBS had a 42.9% average Y-BOCS symptom decrease over 6 months while alpha-band activity in the anterior globus pallidus externus fell.1 The strongest read is a response-marker signal: GPe alpha decreased during effective OCD DBS, but the sample is too small …
Patients with chronic insomnia frequently end up on both a sleep medication and cognitive behavioral therapy for insomnia (CBT-I), and a 2026 AASM meta-analysis of 15 RCTs from Buysse et al. found a clear asymmetry: adding CBT-I to medication helps, while adding medication to CBT-I adds little and may even worsen daytime depression scores.1 Research …
People expect life events to drive adolescent wellbeing — conflicts and breakups push it down, friendships and successes push it up. A 2026 longitudinal twin study from Skaug et al. tested this directly in 2,879 Norwegian twins followed from ages 12 to 20 across three waves and found that genetics, not events, explain most of …
Community forensic mental health services are supposed to bridge secure hospitals, prisons, community psychiatry, and risk management. A 2026 mapping study of England found that these services still vary substantially in structure, referral routes, psychological treatments, and the way they handle restricted patients.1 Research Highlights 32 services were mapped: Freedom of Information responses from NHS …
A 2026 qualitative study from Ethiopia’s Somali Regional State found a harsh care-seeking pattern: mental illness was often recognized only when it looked like visible “madness,” was commonly explained through spiritual causes, and carried stigma severe enough to delay biomedical care.1 Research Highlights 16 interviews shaped the analysis: Warfa et al. interviewed health workers, service …
A 2026 Shanghai study of 1,589 preschoolers found that children sleeping ≤9 hours at night had higher parent-rated anxiety scores than children sleeping >10 hours. The effect sizes were small, but the pattern appeared across total anxiety, physical injury fears, social phobia, obsessive-compulsive symptoms, and generalized anxiety symptoms.1 Research Highlights 1,589 preschoolers were analyzed: Zhang …
A 244-person functional MRI study found no significant evidence that ventral striatum activation during reward anticipation works as an endophenotype — a measurable trait used to connect inherited risk with diagnosed illness — for bipolar and psychotic disorders. Research Highlights The registered hypothesis failed: Barendse et al. found no significant ventral striatum reward-anticipation difference among …