Mental Health DailyResearch. Evidence. Perspective.Published research on Drugs.
A 60-patient randomized trial of lithium loading for acute bipolar I mania reported faster serum lithium attainment than standard titration and a larger 14-day Young Mania Rating Scale (YMRS…
Read articleWhether alcohol, cocaine, nicotine, and cannabis damage the same brain regions or different brain regions has been hard to settle in the addiction-imaging literature. A 2026 ENIGMA Addiction…
Read articleA 2026 eLife computational study modeled classical psychedelics by increasing a network state variable from alpha = 0 to alpha = 1, shifting perception from bottom-up sensory inference towar…
Read articleA 2026 nuMoM2b Heart Health Study analysis tested whether urine-confirmed cannabis exposure 2–7 years after a first pregnancy predicted incident stage II hypertension; it did not: adjusted o…
Read articleA 2026 double-blind randomized controlled trial by Kappes et al. in Psychopharmacology found something the smart-drug users likely wouldn’t have predicted: a single 30 mg dose of methylpheni…
Read articleMost antidepressant pharmacovigilance data come from high-income countries, leaving prescribing patterns and adverse-effect profiles in low- and middle-income countries underdocumented. A 20…
Read articleUntil recently, Alzheimer’s pathology could only be confirmed in living patients via PET imaging or lumbar puncture. Plasma p-tau217 changed that calculus — but how to interpret a positive r…
Read article
